Liverpool won’t play another game for a fortnight after beating Burnley 3-0 as a number of players head off to join their national teams.
Klopp will be praying to avoid any injuries which may disrupt his side’s momentum.
As he nervously waits, he will oversee the group remaining at Melwood.
That will include stand-in ‘keeper, Adrian, Joel Matip, who no longer represents Cameroon, James Milner and Adam Lallana.
Xherdan Shaqiri will also be looking to make an impression after withdrawing himself from Switzerland contention to focus on regaining his place.
Meanwhile, Alisson Becker and Naby Keita are hoping to make significant progress in their respective recoveries.
The English travelling contingent comprises Trent Alexander-Arnold, Joe Gomez, Jordan Henderson and the returning Alex Oxlade-Chamberlain.
The positive news is that both of their games – against Bulgaria on Saturday and Kosovo on Tuesday – will be played on English soil.
Virgil van Dijk and Georginio Wijnaldum, on the other hand, face away games with the Dutch in Germany (Friday) and Estonia (Monday).
Fabinho is back in the Brazil squad alongside Roberto Firmino, but a concern for the Reds might be that their second friendly, against Peru, takes place in the early hours of Wednesday morning ahead of an early kick-off against Newcastle on Saturday.
They will have very little time to prepare.
Elsewhere, Dejan Lovren’s Croatia face Slovakia (Friday) and Azerbaijan (Monday), while Andrew Robertson and Divock Origi could line-up against one another when Belgium meet Scotland on September 9.
Both of Robertson’s games are on British soil, but Origi will have to travel to San Marino with Belgium this week.
A number of players have also been called up at youth-level, including Caoimhin Kelleher (Ireland U21s), Curtis Jones (England U19s) and Rhian Brewster (England U21s).
There are no fixtures pencilled in for Mohamed Salah’s Egypt or Sadio Mane’s Senegal over the next couple of weeks.